THE ROLE OF ERYPTOSIS IN THE PATHOGENESIS OF RENAL ANEMIA: INSIGHTS FROM BASIC RESEARCH AND MATHEMATICAL MODELING

The Role of Eryptosis in the Pathogenesis of Renal Anemia: Insights From Basic Research and Mathematical Modeling

Red blood cells (RBC) are the most abundant cells in the blood.Despite powerful defense systems against chemical and mechanical stressors, their life span is limited to about 120 days in healthy humans and further shortened in patients with kidney failure.Changes in the cell membrane potential and cation permeability trigger a cascade of events tha

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The Role of Plzf in Spermatogonial Stem Cell Maintenance and Differentiation: Mapping the Transcriptional Dynamics and Key Interactions

Spermatogonial stem cells (SSCs) sustain and modulate spermatogenesis through intricate signaling pathways and transcription factors.Promyelocytic leukemia zinc-finger (Plzf, also known as Zbtb16) has been identified as a critical transcription factor influencing various signaling and differentiation pathways.Plzf plays a pivotal role in regulating

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Accurate Discharge Estimation Based on River Widths of SWOT and Constrained At-Many-Stations Hydraulic Geometry

River discharge monitoring is an important component of the hydrology objectives of Surface Water and Ocean Topography mission (SWOT).River discharge can be estimated Solely using river widths and At Many-stations Hydraulic Geometry (AMHG), but the accuracy is low due to the parameters of At a-station Hydraulic Geometry (AHG) given by AMHG deviate

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